![]() ![]() ![]() Percocet is available in four different strengths: 2.5mg oxycodone/325mg acetaminophen, 5mg oxycodone/325mg acetaminophen, 7.5mg oxycodone/325mg acetaminophen, and 10mg oxycodone/325mg acetaminophen. Vicodin ES contains 7.5mg hydrocodone and 300mg acetaminophen and Vicodin HP contains 10mg hydrocodone and 300mg acetaminophen. FormulationsĪbbVies's Vicodin is available as a tablet containing 5mg hydrocodone and 300mg acetaminophen. Both oxycodone and hydrocodone can cause physical and psychological dependence, and tolerance can develop on repeated administration (tolerance is when the same dosage no longer provides the same level of pain relief). The incidence of constipation appears higher with hydrocodone. Hydrocodone-related side effects are similar to oxycodone-related side effects and include constipation, nausea, vomiting, itching and drowsiness. Are there any differences in side effects? Non-narcotic pain relievers (such as acetaminophen, NSAIDs) and non pharmacological therapy (such as acupuncture, cognitive behavioral therapy) are the preferred options for the relief of chronic non-cancer related pain. Opioid-containing medications should only be used for cancer-related pain or as a last resort for moderate-to-severe pain that is unresponsive to less potent pain-relief medicines. Vicodin, Percocet, and other similar opioid-type pain-relieving tablets should NOT be used long-term for chronic non-cancer related pain relief, in fact guidelines actively discourage this practice because of the risk for addiction, dependence and abuse. Which one is better long-term?īoth Vicodin and Percocet should only be used short-term, unless given for unremitting, cancer-related pain. Hydrocodone is also effective as a cough suppressant. There does appear to be some controversy over the potency on a mg for mg basis between hydrocodone and oxycodone however, one study found 5mg oxycodone to be just as effective as 5mg of hydrocodone. Neither Vicodin nor Percocet are available as abuse-deterrent forms. Studies have shown no differences in the pain-relieving properties of hydrocodone and oxycodone however, oxycodone appears to have a higher abuse liability potential than hydrocodone, which means Percocet is more likely to be abused. Is oxycodone more effective than hydrocodone, or more likely to be abused? Both hydrocodone and oxycodone are available as single ingredient tablets (hydrocodone oxycodone ) and in many cases prescribing a single-ingredient opioid product along with additional acetaminophen tablets may allow improved pain control with less risk of side effects compared with giving a combination tablet such as Vicodin or Percocet. What are the benefits of acetaminophen in these tablets?Īdding acetaminophen to an opioid improves that opioid's pain-relieving capabilities however, the amount of acetaminophen contained in both Vicodin and Percocet is too small to provide an effective dose when tablets are taken at the recommended dosages. ![]() The opioid in Vicodin is hydrocodone and the opioid in Percocet is oxycodone. Both contain acetaminophen and an opioid-type ingredient. Vicodin and Percocet are both combination pain-relieving tablets. Percocet is more likely to be abused because it contains oxycodone, which appears to have a higher abuse liability potential than hydrocodone which is contained in Vicodin. ![]()
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